Detection of KRAS mutations in colorectal cancer with Fast COLD-PCR
نویسندگان
چکیده
منابع مشابه
Detection of KRAS mutations in colorectal cancer with Fast COLD-PCR.
Patients with metastatic colorectal carcinoma (mCRC) carrying activating mutations of the KRAS gene do not benefit from treatment with anti-epidermal growth factor receptor (EGFR) monoclonal antibodies. Therefore, KRAS mutation testing of mCRC patients is mandatory in the clinical setting for the choice of the most appropriate therapy. Co-amplific...
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ژورنال
عنوان ژورنال: International Journal of Oncology
سال: 2011
ISSN: 1019-6439,1791-2423
DOI: 10.3892/ijo.2011.1221